The trainer feels his side were hindered by fitness problems in their home loss against the side.
Jose Mourinho says it felt like Tottenham went into a gunfight without bullets in their defeat to RB Leipzig from the Champions League.
Spurs went 1-0 down at home through Timo Werner’s punishment at the first leg of this last-16 tie.
The Premier League side were without star attacker’s Harry Kane and Son Heung-min, while Erik Lamela returned from injury to attribute for the past twenty minutes.
And Mourinho believes his side did the best they could despite their exercise problems and believes they could recover in the second leg in Germany on March 10.
“Let us be loyal to the boys and state that they did whatever they could do,” he advised Sky Sports following the game.
“Lamela, do you know how many training sessions he had with the group? Zero. Direct from trauma, to regaining on the pitch with the physios to 20 minutes of a match in the Champions League.
“That is our staff. You can look at it and see two viewpoints. 1 perspective is of an wonderful group with amazing guys that try everything, from the other side you see how we’re in this moment.
“You look at the other men, they play [Patrik] Schick, [Timo] Werner and [Christopher] Nkunku. Nkunku is tired, get out, on comes [Emil] Forsberg. Schick is tired, come off, there is [Yussuf] Poulsen.
“That is our situation, it is like going to a fight with a gun without bullets. We did what we can do, and I believe when we scored before them the game will be different.
“You can tell me we had fortune in certain minutes, but I disagree.
“What I am concerned about isn’t the 1-0, because that’s an open result, we could go there and win the tie.
“What worries me is that these are our players for another… I don’t know how many games. We must play in two days.
“We could see Lucas absolutely lifeless, [Steven] Bergwijn absolutely lifeless, [Giovani] Lo Celso dead.
“We’re really in trouble. If this was only for this game, I’d say ‘Okay no issue, 1-0, what’s open’. What worries me is that people have Premier League and FA Cup to play too and this is our situation.
“I can’t be happier to have men like them with the constraints we have.”
Spurs are in action again on Saturday when they travel to Stamford Bridge to take on London rivals Chelsea. And Mourinho expects Frank Lampard’s team to be in far better shape than his side when they meet in the first kick-off.
He added: “But here we go, and Chelsea drinking hot water with lemon and watching the match on TV. On Saturday morning, thank you very much for the selection, Saturday morning we’re there again.”